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009, most of which is due to Pluto,probably a sampling fluctuation due to Pluto's sample size being lessthan one fifth of the others. When Francoise examined the astrologers keywords for the five Gauquelinplanets, she noted that a keyword "given by only one astrologer is mostoften contradicted ", whereas one given by"more than one astrologer . is most often confirmed" p. 57. Which iscompatible with a Gauquelin bias arising from his reading many astrologybooks instead of just a few. On average 44% of keywords were on theGauquelin trait list for that planet, 22% were on the trait list for adifferent planet, and the remaining 34% were on neither again aresult compatible with the trait list having been shifted by Gauquelinbias in the direction of agreement with planetary keywords.

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, 2011; Lee et al. , 2012, demonstrating the inaccuracy of mapping data. After gene identification, mutations were also identified in pure BFIS families Ono et al. , 2012, as well as in occasional cases with hemiplegic migraine Dale et al. , 2012. This confirmed that mutations in the same gene can cause heterogeneous phenotypes, suggesting a genetic complexity previously unexpected for Mendelian disorders Schmidt et al. , 2012. Subsequently, the same WES approach has been successfully used to identify four novel genes causative of late onset PTD, as previously described. Genome wide association studies, on the other hand, aim at identifying polymorphic variants acting as risk factors for complex diseases via large scale, population based studies. In movement disorders, this approach has been largely adapted to PD, although the number of significant hits has been unexpectedly low and only few genes, such as SNCA, MAPT, and LRRK2, have been found to harbor variants robustly associated with the disease. A recent meta analysis of GWAS studies in PD identified 17 additional disease risk loci which surpassed the threshold for genome wide significance, all with low odds ratios Kumar et al.

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99 a month, offers unlimited access to a catalogue of more than 650,000 ebooks, as well as more than 2,000 audiobooks from Amazons Audible subsidiaryAmazon says that authors will be paid each time someone reads more than 10% of one of their books through the new service. An inquiry into the market for electronic books e books in the UK should be launched, the Publishers Association has said. In a document setting out its recommended range of policies the next UK government should adopt, the trade body said that an inquiry should seek to better facilitate competition in both the e books market and the online market for print books, which it said should be treated as separate markets. OrangeDigit is one Korean startup getting into the interactive eBook space in a big way. Using multi layered designs that allow for multimedia, images and even music to be presented to readers as they consume literature, the new format theyve come up with allows a new way of interfacing with what we read Ebooks up 7 per cent. Overall revenues are up slightly for U. S. trade books, according to monthly and year to date figures released today by the Association of American Publishers AAP Online retailer Amazon. com Inc is in talks with a number of Dutch publishers to sell e books in the Netherlands, the Financial Times reported, citing a Dutch publisher . Clearly the company thinks there is a place out there for a premium e reader and, while we cant vouch for the vibrancy of the high end e reader market, we can confirm that Amazon has put together a stunner of a device. Now all Amazon has to do is convince someone that any e reader, even one as lovely as the Voyage, is worth $200.

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